Mounjaro vs Zepbound: What's the Difference?
Both are tirzepatide, approved for different things. Here is the honest difference.
The short answer
Mounjaro and Zepbound are both tirzepatide, made by Eli Lilly. Mounjaro is FDA-approved to treat type 2 diabetes. Zepbound is FDA-approved for chronic weight management and for obstructive sleep apnea in adults with obesity. Same molecule, different approved uses.
Quick comparison
| Feature | Mounjaro | Zepbound |
|---|---|---|
| Active ingredient | Tirzepatide | Tirzepatide |
| Maker | Eli Lilly | Eli Lilly |
| FDA-approved for | Type 2 diabetes | Chronic weight management, plus obstructive sleep apnea in adults with obesity |
| How it is taken | Injection | Injection |
| Available as | Brand-name medication | Brand-name medication |
| At New Hope Weight Loss | Not dispensed here | Not dispensed here |
How tirzepatide differs from semaglutide
Tirzepatide acts on two appetite-hormone pathways (GIP and GLP-1); semaglutide acts on one (GLP-1). In trials of the brand drugs, tirzepatide produced larger average weight loss.
Ready to start?
$199 Skeptics' Trial, see if it works for you
One-time $199 trial with physician evaluation and, only if a prescription is approved and the dispensing pharmacy can fulfill it for the patient's location, one month of compounded semaglutide; the pharmacy confirms packaging and shipping details before fulfillment. No long-term commitment. Standard care starts with a $119 physician review; medication is separate, and compounded semaglutide programs start at $166/month.
Start the 30-day trialWhat the evidence shows
In SURMOUNT-1 (NEJM 2022; PMID 35658024), adults on tirzepatide 15 mg lost an average of about 20.9% of body weight at 72 weeks versus 3.1% on placebo. That studied the brand medication; individual results vary.
How this relates to what we offer
New Hope Weight Loss does not dispense Mounjaro or Zepbound. The dispensing pharmacy label identifies the compounded preparation as tirzepatide. It is a different product from FDA-approved brands, is not FDA-approved or brand-identical, and results vary. A $119 review decides whether it is appropriate for you.
What you can start today at New Hope Weight Loss
After a one-time $119 medical review with Dr. Sharma, eligible patients begin a physician-supervised program with compounded semaglutide from $166 a month or compounded tirzepatide from $233 a month, with a $199 one-month Skeptics' Trial. Compounded semaglutide and tirzepatide are not FDA-approved or brand-identical and have not undergone FDA premarket review for safety, effectiveness, or quality. Results vary. Any prescription depends on individualized medical review and lawful pharmacy fulfillment for the patient's location. Care is in person in Orange County and by telehealth for eligible patients in California.
Frequently asked questions
Are Mounjaro and Zepbound the same?
Both are tirzepatide from Eli Lilly. Mounjaro is FDA-approved for type 2 diabetes; Zepbound for weight management and obstructive sleep apnea in adults with obesity. Same molecule, different approved uses.
Is tirzepatide stronger than semaglutide?
In trials of the brand drugs, tirzepatide produced larger average weight loss (up to about 20.9% in SURMOUNT-1) than semaglutide (about 14.9% in STEP 1). It works on two hormone pathways instead of one. The best choice still depends on your situation.
Is compounded tirzepatide the same as Zepbound or Mounjaro?
No. It is a separately prepared compounded product that is not FDA-approved, not brand-identical, and has not undergone FDA premarket review for safety, effectiveness, or quality. Results vary. We never claim it is the brand.
Does Zepbound help with sleep apnea?
Zepbound is FDA-approved for obstructive sleep apnea in adults with obesity, based on the SURMOUNT-OSA trial. That indication applies to the brand product.
Does New Hope Weight Loss offer Mounjaro or Zepbound?
We do not dispense the brand products. We offer physician-supervised compounded tirzepatide from $233/mo after a $119 review, with honest framing about what compounded means.
This article is informational only and not medical advice. Speak with a licensed physician before starting or changing any GLP-1 therapy. Individual results vary. New Hope Weight Loss is a physician-supervised medical weight loss clinic in Costa Mesa, CA. Eligibility for treatment is determined during the medical consultation. Compounded semaglutide and compounded tirzepatide are not the same products as Wegovy®, Ozempic®, Mounjaro®, or Zepbound®.